Selank

Selank is a synthetic heptapeptide primarily used to reduce anxiety and stress while simultaneously enhancing cognitive function without causing sedation or dependence.

Developed in Russia as an analog of the immune peptide tuftsin, it works by modulating neurotransmitters like GABA, serotonin, and dopamine, and by increasing Brain-Derived Neurotrophic Factor (BDNF) to support neuroplasticity.

Key benefits include:

• Anxiety Relief: Clinical trials show it reduces symptoms of generalized anxiety disorder and PTSD effectively, similar to benzodiazepines but without the risk of addiction, tolerance, or withdrawal.
• Cognitive Enhancement: It improves focus, attention, memory, and learning capacity, making it useful for brain fog, ADHD symptoms, and age-related cognitive decline.
• Mood Stabilization: By balancing serotonin and dopamine levels, it helps alleviate depressive symptoms and improves emotional resilience and motivation.
• Stress Adaptation: It helps normalize cortisol responses in chronically stressed individuals, supporting adrenal function and reducing mental fatigue.
• Sleep Quality: While not a sedative, it may improve sleep architecture and regulation of circadian rhythms through GABA and serotonin modulation.
• Immune Modulation: It exhibits immunomodulatory effects by regulating cytokine expression, potentially helping to fight viral infections and reduce neuroinflammation.

Selank is typically administered via intranasal spray or subcutaneous injection, with standard dosages ranging from 250–500 mcg daily.